Radka Saldova-Fahey, PhD - Cancer Research

Current Area of Interest


I joined the Glycobiology group in May 2005 as a Research Assistant, defended my PhD in Institute of Chemical Technology Prague in November 2007 and continue as a Postdoctoral Research Assistant.

My main research interest is focused on cancer. I am currently working on various glycosylation based approaches to find biomarkers for cancer. The main techniques that I have applied in my project are N-glycan release from whole serum glycoproteins of cancer patients and controls followed by glycan sequencing using HPLC and exoglycosidase digestions. Preeliminary results from the glycan analysis have led to electrophoresis- 1D and 2D gels, immunochemical methods and protein purification techniques. I am also now applying these techniques together with epigenetics analyses with the ovarian cell line OVCAR3, to further understand the glycosylation changes contributed by the tumour. I am also analyzing glycosylation in mouse inflammation model to understand role of inflammation in cancer and its effect on glycosylation.



Contact Information

Email:follow this link