- Pauline M. Rudd - PI
- Barbara Keegan - PA/Administrator (to Professor Pauline M. Rudd)
Margaret Doherty, PhD - Technology Development
Principal Investigator
Post-Docs
- Giorgio Carta - Bioinformatics
- Eoin Cosgrave - Fc Receptor Glycobiology
- Margaret Doherty - Technology Development
- Eugene Dempsey - Cell signalling in Cancer
- Rebecca Duke - Glycobiology of O-linked glycans
- Mark Hilliard - Mass Spectrometry Development and Analytics
- Jayesh Kattla - Training and Research
- Karina Marino- Alimentary Glycoscience Research Cluster
- Niaobh O'Donoghue - Lab Manager
- John O'Rourke - Bioinformatics
- Oscar Potter - Technology Development
- Radka Saldova-Fahey - Glycobiology and Cancer
- Michael Schomberg - Technology Development
- Weston Struwe - Mass Spectrometry Development and Analytics
- Jayne Telford - Glycobiology and Disease
- Tharmala Tharmalingam - Reproductive Biology Research Cluster
Research Assistants
- Barbara Adamczyk - Glycobiology and Disease
- Patrick Jennings - Glycobiology and Disease
- Joanne Withers - Glycobiology and Disease
PhD Student
- Marie Galligan- Statistics
Former members
- Jonathan Bones
- Matthew Campbell
- Li Liu
- Jodie Abrahams
- Jennifer Byrne
- Marion Boland
- Ronan Kelly
- Ciara McManus
- Natalia Artemenko
Current Area of Interest
My role within NIBRT is to further advance our current high-throughput technology and develop a fully automated system utilizing a robotic platform.
Current analytical approaches to obtaining detailed product quality data require extensive sample preparation (e.g. to release and label glycans) and analysis (e.g., HPLC or CE-LIF, LC-MS peptide mapping), which delay the generation of key information. The ability to obtain rapid information, particularly regarding glycoform structures on-line would greatly enhance process development and optimization. Ultimately the robotic platform will be interfaced directly with processing operations to enable monitoring of cell culture conditions and the acquisition of real-time information to ensure optimized product quality.
Other aspects of my post include development and optimization of methodologies for O-glycan release and analysis, N-glycan analysis, beta testing of innovative products to facilitate glycan analysis, development of proprietary databases for IgG analysis and technology transfer.
Other Information
Contact Information
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